枞阳县长沙乡鼠类抗药性研究  

Study on Rat Anticoagulant Resistance in Changsha Area, Zongyang County

作　　者：刘春生[1] 郭世坤[1] 吴万能[1] 张家林[1] 杨健华[1] 徐立[1] 朱汉平[1] 张孝让 吴道余 王根生 刘百龄 

机构地区：[1]安徽省卫生防疫站,安庆市卫生防疫站,枞阳县卫生防疫站

出　　处：《中国媒介生物学及控制杂志》1994年第6期437-439,共3页Chinese Journal of Vector Biology and Control

摘　　要：按全国鼠类抗药性监测协作组规定的方法，以极阳县长沙乡为试点，１９９１年１０～１１月对２２只褐家鼠（♂９，♀１３）、１９９３年１１～１２月对２４只褐家鼠（♂１４，♀１０）和１４只黄胸鼠（♂８，♀６）进行了抗药性监测．结果显示，１９９１年褐家鼠平均致死剂量为９．６３ｍｇ／ｋｇ，致死天数为４．５天，抗性发生率为零；１９９３年褐家鼠平均致死剂量为１９．５４ｍｇ／ｋｇ．致死无数为５．３５天，存活鼠１只，存活剂量为２７．８ｍｇ／ｋｇ，抗性发生率为４．１７％。两年间致死剂量平均增加１倍，致死天数平均延长近１天。黄胸鼠平均致死剂量为１４３．８１ｍｇ／ｋｇ，平均致死无数为８．４３天，未发现抗性鼠。本文提示，使用抗凝血灭鼠剂达６年以上地区，应加强抗性监测，防止抗性鼠出现。The authors monitored the anticoagulant resistance of Rattus norvegicus and Rattus flavipectus, from Oct. to Nov. 1991 and from Nov.to Dec. 1991. 22(♂9,♀13)and in l993 24(♂14,♀10)Rattus nortIegiclIs and 14(♂8,♀6)Rattusflavipectus was tested The result shows that for Rattus norvegicus in 1991 the average lethal dosage is 9.63mg/kg, death happens 4.5 days after the distribution. The anticoagulant resistance rate is zero However in 1993 the average lethal dosage changed to 19.54mg/kg, the average death happens after 5.35 days with one survival.The average lethal dosage doubled in two years and the duration before death prolonged l1early one day, For Rattus flavipectus the averge lethal dosage is 143.81 mg/kg, average duration before death is 8.43 days and no survital found. The author sugest that the anticoagulant resistance test must be given after six years of distribution in order to prevent the anticoagulant resistance.

关 键 词：褐家鼠 黄胸鼠 抗药性 防治 

分 类 号：R184.35[医药卫生—流行病学] R979.8[医药卫生—公共卫生与预防医学]