银菊颗粒的质量控制  

The Quality Control of Yinju Granule

作　　者：彭晓青[1] 苏维辉[1] 刘炜[1] 

机构地区：[1]广州市第一人民医院,广州510180

出　　处：《海峡药学》2005年第2期11-13,共3页Strait Pharmaceutical Journal

摘　　要：目的建立银菊颗粒的质量标准。方法采用系数倍率法测定银菊颗粒中绿原酸的含量,采用Q10法预测银菊颗粒的有效期。结果绿原酸的线性范围为3.3～26.4μg·mL-1(r=0.9999),平均回收率为101.12%,RSD为1.80%。银菊颗粒的有效期为12个月。结论本文方法简便、快速、准确,可用于银菊颗粒的质量控制。OBJECTIVE To establish the quality standard of Yinju Granule.METHODS The content of chlorogenic acid was determined by K-ratio method.The period of validity of Yinju Granule was forecasted by Q 10 method .RESULTS The linear range of chlorogenic acid was 3.3～26.4μg·mL -1(r=0.9999).The average recovery was 101.12% with RSD of 1.80%. The period of validity of Yinju Granule was 12 months.CONCLUSION The method is simple ,fast and accurate.It can be used for the quality control of Yinju

关 键 词：系数倍率法 绿原酸 Q10法 有效期 

分 类 号：R972.4[医药卫生—药品] R927.11[医药卫生—药学]