洛美沙星胶囊的铽增敏化学发光法测定  

Determination of Lomefloxacin Capsules by Terbium Sensitized Chemiluminescence Method

作　　者：石杰[1] 赵开楼[1] 宋庆国[1] 李力[1] 曹丰璞[1] 

机构地区：[1]郑州大学化学系,河南郑州450052

出　　处：《中国医药工业杂志》2005年第5期298-299,共2页Chinese Journal of Pharmaceuticals

基　　金：河南省科技攻关项目(O324420044)

摘　　要：利用Tb3+能大幅增强Ce4+-H2SO3-洛美沙星体系的化学发光,采用流动注射技术,建立了化学发光法测定洛美沙星胶囊含量。线性范围为1.0×10-8～3.0×10-5g/ml。平均回收率为97.1%。Based on the chemiluminescence reaction of Ce 4+ -H 2 SO 3 -lomefloxacin could be sensitized by Tb 3+ , a chemiluminescence method for the determination of lomefloxacin capsules was established by flow-injection. The calibra- tion curve was linear in the concentration range of 1.0×10 -8 - 3.0×10 -5 g/ml. The average recovery was 97.1%.

关 键 词：洛美沙星 铽 增敏化学发光 流动注射 测定 

分 类 号：TQ460.72[医药卫生—药物分析学] O657.39[化学工程—制药化工]