原发性肺动脉高压的诊断和治疗  

Diagnosis and Treatment of Primary Pulmonary Hypertension

作　　者：白淑霞[1] 高伟[1] 黄美蓉[1] 李筠[1] 余志庆[1] 杨健萍[1] 

机构地区：[1]上海第二医科大学附属新华医院上海儿童医学中心,上海200127

出　　处：《实用儿科临床杂志》2005年第5期454-455,共2页Journal of Applied Clinical Pediatrics

摘　　要：目的探讨儿童原发性肺动脉高压(PPH)的临床诊治特点。方法对收治15例PPH患儿的临床资料及治疗、转归进行分析。结果15例均有不同程度心功能不全症状、体征,心电图示右室肥厚,超声心动图示右房、右室大、肺动脉增宽。14例行心导管检查显示肺动脉压增高、肺小动脉楔压正常。PPH预后差,仅3例治疗后活动耐力增加。结论PPH症状无特异性,心导管检查在诊断中具有重要作用。PPH缺乏有效治疗,血管扩张剂和钙通道阻滞剂有一定疗效。Objective To investigate the diagnosis and treatment of primary pulmonary hypertension(PPH) in children. Methods The clinical data of 15 patients with PPH were summed up and analysed. Results Fifteen patients all had the symptoms and signs of heart failure,the electrocardiogram exhibited right ventricular enlargement,the echocardiography demonstrated enlargement of the right atrium and ventricle and pulmonary artery enlargement, the cardiac catheterization in 14 patients showed pulmonary artery hypertension and normal pulmonary capillary wedge pressure. The prognosis of PPH was bad, the activity resistance was increased only in 3 patients after nifedipine treatment. Conclusions The symptom of PPH have not speciality, its diagnosis depends on cardiac catheterization, its treatment effect is not satisfactory,calcium channel blockers and other vasodilator are helpful in the treatment of PPH.

关 键 词：肺动脉高压 原发性 诊断 治疗 

分 类 号：R725.4[医药卫生—儿科]