垂体后叶素在胆道手术中的应用  

THE APPLICATION OF PITRESSIN IN BILIARY SURGERY

作　　者：耿协强[1] 周致益[1] 樊献军[1] 韩天民[1] 

机构地区：[1]中国人民解放军59中心医院肝胆外科

出　　处：《中国普通外科杂志》1994年第1期20-21,共2页China Journal of General Surgery

摘　　要：１９８６年１２月至１９９０年３月，我院在１８例合并有门静脉高压的肝胆管绍石病人术中加用垂体后叶素，对降低门静脉压，减少术中出血，顺利完成手术取得了满意效果。作者认为由周围静脉，一次性滴注垂体后叶素２０ｕ，滴速０．４～０．５ｕ／ｍｉｎ，效果较佳。用药后门静脉压下降可维持２～３小时，基本可完成胆道复杂性手术操作步骤。用药指征是：门静脉压＞２．３５ｋＰａ（２４０ｍｍＨ２ｏ）；无出血史；术中用药后门静脉压下降明显，肝内胆管有多支充满型结石；需作高位狭窄服管整形者。若门静脉高压合并脾功能亢进，宜先行脾切除及简单胆道引流术，再二期完成胆道复杂手术。he article reports that the application of pitressin during the operation of 18 palients withhepoatolithiasis complicated with portal hypertension, led to satisfactory results in dccrcasing portalpressure and reducing hemorrhage at operation. from December 1986 to March 1990. The writersdiscussed the selection of patient and the application curative effect,adaptation and the prevention ofthe complications of pitressin. The authors advise to drip pitressin 20u through a peripheral vein onlyonce at the rateof 0. 4u to 0. 5u a minute ,and it was found that the decrease of portal pressure may bemaintained for 2 to 3 hours,so one can finish complicated biliary tract operations.Tne indications ofthe pitressin application. ①when portal pressure exceeds 2. 35kpa (240nimH2O ) ; ②patients who hadno history of hemorrhage;③decrease of portalpressure at operation is marked after the use of the drug ;④those who need reconstruction of superior stenotic biliary tracts because they have many ductus filledwith calculi.

关 键 词：垂体后叶素 门脉高血压 肝胆管结石 

分 类 号：R657.405[医药卫生—外科学]