环孢素A在尸体肾移植中应用的体会  

AN EXPERIENCE WITH THE USE OF CsA IN CADAVERIC RENAL TRANSPLANTATION

作　　者：余大敏[1] 齐范[1] 张时纯[1] 申鹏飞[1] 黄福溥[1] 王维鑫[1] 蒋先镇[1] 顿金庚[1] 张向阳[1] 周芳坚[1] 齐琳[1] 唐正严[1] 

机构地区：[1]湖南医科大学附属湘雅医院泌尿外科,410008

出　　处：《中国普通外科杂志》1994年第6期358-360,共3页China Journal of General Surgery

摘　　要：本文报告自1992年1月至1994年8月我院17例尸体肾移植应用CsA的体会。本组总的人/肾存活率为81.3%/75.o%。感染仍是肾移植患者死亡的主要原因。在环孢素时代,急性排斥反应(AR)的发生率下降,其表现较不典型且轻微。本组HLA配型与AR发生率的相关性不明显。本文对AR的诊断与治疗以及AR与CsA肾中毒的鉴别进行了探讨。CsA was used from Janurary 1992 to August 1994' in 17 cases of cadaveric renal transplantation. The total survival rate of the patient and the kidney was 81. 3% and 75. 0% respectively. In the CsA age, infection was still the main cause of recipient death. Meanwhile, acute rejection (AR) rate became lower and the manifestation of AR became more atypical and milder. There was no correlation found between HLA matching and AR incidence in our group. The diagnosis and management of AR as well as its differentiation with CsA nephrotoxici-ty were also discussed.

关 键 词：肾移植 排斥 环孢素A 尸体 

分 类 号：R699.2[医药卫生—泌尿科学]