植物生物转化技术在药用活性成分生产及新药开发中的应用  

The application and perspective of plant biotechnology in biotransformation of medicinal constituents

作　　者：于荣敏[1] 邱立鹏[2] 赵昱[3] 孙平华[1] 叶文才[1] 姚新生[1] 

机构地区：[1]暨南大学药学院,广州510632 [2]沈阳药科大学,沈阳110016 [3]浙江大学药学院,杭州310031

出　　处：《中国新药杂志》2005年第4期407-412,共6页Chinese Journal of New Drugs

摘　　要：论述了利用植物生物技术(如植物细胞培养、转基因组织/器官、植物酶系统等)进行药用活性成分生物转化的发展概况,并对其发展前景进行了评述性展望。植物生物转化技术可能是创制具有自主知识产权新药的新途径。New types of medicines, providing prevention and treatment against diseases for which pharmacotherapy was previously impossible, have been developed thanks to the achievements of plant biotransformation. This review details the history, current status and perspectives of the plant biotechnology, including plant cells, transgene tissues/organs, and enzyme systems cultures.

关 键 词：生物转化 细胞培养 转基因 活性成分 新药研制 

分 类 号：R282.2[医药卫生—中药学] R931.71[医药卫生—中医学]