用BMM系统去除乙肝病毒颗粒的研究  

Study on Elimination of Dane Particles Using BMM System

作　　者：王子柱[1] 杨长岭 王丽霞[1] 倪道明[1] 唐巧英[1] 赵铠[1] 

机构地区：[1]卫生部北京生物制品研究所,北京100024

出　　处：《中国生物制品学杂志》1994年第2期67-69,共3页Chinese Journal of Biologicals

摘　　要：乙肝血源疫苗蔗糖离心后样品，经日本BMM系统过滤后，对蛋白含量和乙肝表面抗原活性没有明显影响，但对去除乙肝病毒颗粒有明显效果，因此，进一步提高了乙肝疫苗的回收率和安全性。The samples of plasma-derived hepatitis B vaccine after sucrose gradient centrifugation were filtered by BMM system (made in Japan). The result showed that the procedure had no remarkable influence on protein content and HBsAg astivity, but showed significant effect on elimination of Dane particles. It suggested that, by using the system, the recovery rate and safety of hepatitis B vaccine could be further improved.

关 键 词：日本BMM系统 乙型肝炎病毒 颗粒 

分 类 号：R392－33[医药卫生—免疫学]