Synthesis and Characterization of ABBA Block Copolymer of Glycolide and ε-Caprolactone  

作　　者：CHENLi CHENXue-si DENGMing-xiao JINGXia-bin 

机构地区：[1]StateKeyLaboratoryofPolymerPhysicsandChemistry,UhangchunInstituteofAppliedChemistry,ChineseAcademyofSciences,Changchun130022,P.R.China [2]StateKeyLaboratoryofPolymerPhysicsandChemistry,UhangchunInstituteofAppliedChemistry,ChineseAcademyofSciences,Changchun130022,P.R.China／／FacultyofChemistry,NortheastNormalUniversity

出　　处：《Chemical Research in Chinese Universities》2005年第3期340-344,共5页高等学校化学研究（英文版）

基　　金：SupportedbytheNationalNaturalScienceFoundationofChina(No.50273038)andNationalFundforDistinguishedYoungScholar(No.50425309).

摘　　要：A biodegradable ABBA block copolymer was synthesized via the ring-opening co-polymerization of ~ε-caprolactone(CL, B) and glycolide(A) by means of step polymerization in the presence of ethylene glycol as an initiator and stannous octanoate as a catalyst at 110 ℃ for 48 h. The molecular length of the PCL pre-polymer(BB) could be adjusted by controlling the molar ratio of the ethylene glycol initiator to ε-caprolactone monomer. The structure and the composition of the block copolymer were determined by the weight ratio of the monomer glycolide(A) to PCL pre-polymer(BB). The block copolymers were characterized by ~ 1H NMR, GPC, DSC and X-ray. The results confirm the successful synthesis of an ABBA block copolymer.A biodegradable ABBA block copolymer was synthesized via the ring-opening co-polymerization of ~ε-caprolactone(CL, B) and glycolide(A) by means of step polymerization in the presence of ethylene glycol as an initiator and stannous octanoate as a catalyst at 110 ℃ for 48 h. The molecular length of the PCL pre-polymer(BB) could be adjusted by controlling the molar ratio of the ethylene glycol initiator to ε-caprolactone monomer. The structure and the composition of the block copolymer were determined by the weight ratio of the monomer glycolide(A) to PCL pre-polymer(BB). The block copolymers were characterized by ~ 1H NMR, GPC, DSC and X-ray. The results confirm the successful synthesis of an ABBA block copolymer.

关 键 词：Biomaterial POLYGLYCOLIDE Poly(ε-caprolactone) Ring-opening polymerization Block copolymer 

分 类 号：O633.14[理学—高分子化学]