正交试验优选滋肾颗粒的提取工艺  

Extracting Techniques for Optimizing Zi Shen Granule by Orthogonal Text

作　　者：侯励[1] 黄佩琨[1] 李志国[1] 

机构地区：[1]暨南大学附属第一医院,广州510630

出　　处：《中药材》2005年第5期423-425,共3页Journal of Chinese Medicinal Materials

摘　　要：目的:优选滋肾颗粒的提取工艺。方法:以浸膏得率和总蒽醌含量为指标,采用L9 (3)4 正交试验对滋肾颗粒的提取工艺进行优选。结果:最佳提取工艺为提取时间2h、1 .5h,加水8倍量,提取2次,水溶液浓缩至相对密度1. 10,加乙醇至含醇量为70%,静置24h。结论:优选后的提取工艺、合理、稳定,适用于大生产。Objective:To optimize the extracting techniques for Zi Shen Granule.Methods:By taking the rate of extractum and the total of anthraquinone as the indexes components,the extraction techniques were optimized for Zi Shen Granule through L 9(3)4 orthogonal text.Results:The best condition is twice extraction by 2h or 1.5h,to add octuple water.Then the water solution was concentrated to relative concentration 1.10,and adds ethanol to 70% alcohol Concentration,then stewing 24h.Conclusion:The optemized extraction technique is rational and jarless and ideal for mass production.

关 键 词：正交试验 优选 颗粒 滋肾 最佳提取工艺 总蒽醌含量 浸膏得率 提取时间 相对密度 溶液浓缩 含醇量 24h 

分 类 号：R284.2[医药卫生—中药学] R944.5[医药卫生—中医学]