SARS治疗中甲泼尼龙注射液应用的探讨  

Methylprednisolone in Treament of SARS

作　　者：代伟[1] 董军[1] 曹秀堂[1] 高筠[1] 王玮[2] 

机构地区：[1]解放军总医院,北京100853 [2]解放军307医院,北京100039

出　　处：《中华医院感染学杂志》2005年第5期487-489,共3页Chinese Journal of Nosocomiology

基　　金：全军非典型肺炎防治重大科技项目(03F022)

摘　　要：目的探讨甲泼尼龙注射液在传染性非典型肺炎(SARS)治疗过程中的用药规律与特点. 方法回顾分析2003年5～6月收治的680例非典型肺炎的临床诊断治疗用药信息. 结果 680例患者使用甲泼尼龙注射液的有408人,占60%,根据使用剂量分为高低量不等的8个组, 291人从入院第1天开始连续用药,376人平均每日用药剂量≤80 mg,平均用药天数(11.1±7.5)d. 结论激素类用药呈现一定的用药规律,为防止加重继发感染,何时开始用药,每次用药的剂量、频次、疗程及方式都应根据患者的具体情况决定用药方案,以达到提高治愈率,降低感染率的目的.OBJECTIVE To study the distinguishing features of methylprednisolone in the treatment of SARS. METHODS The medical information of 680 cases of SARS from May to Jun 2003 were collected and analyzed. RESULTSFour hundred and eight of 680 SARS patients were treated with methylprednisolone, which were 60%. The SARS patients were divided into 8 groups according to different medicine dosage, 291 SARS patients were treated with the medicine continuously from the first day on. The medicine dosage of 376 SARS patients was less than 80 mg on average. The length of time using the medicine was (11.1±7.5)d. CONCLUSIONS The use of hormonehas a regular pattern. In order to avoid sharpening the secondary infection, improve the rate of cure and reduce the rate of infection, the treatment with the medicine is determined by when the use of the medicine starts, the medicine dosage each time, frequency, the period of treatment and fashion.

关 键 词：传染性非典型肺炎(SARS) 甲泼尼龙 

分 类 号：R183.3[医药卫生—流行病学]