含功能性羟基的温敏性聚(N-异丙基丙烯酰胺)微凝胶的制备及性能研究  

PREPARATION AND STUDIES OF TEMPERATURE SENSITIVE POLY( N-ISOPROPYLACRYLAMIDE) MICROGELS CONTAINING FUNCTIONAL HYDROXYL GROUPS

作　　者：马晓梅[1] 朱路[1] 席靖宇[1] 赵喜安[1] 唐小真[1] 

机构地区：[1]上海交通大学化学化工学院

出　　处：《高分子学报》2005年第2期197-202,共6页Acta Polymerica Sinica

摘　　要：采用两步合成路线合成了二缩三乙二醇单甲基丙烯酸酯 (TREGMA) ,并对其结构进行了表征 ;利用无皂乳液聚合法使N 异丙基丙烯酰胺 (NIPAM)、TREGMA和N ,N 亚甲基双丙烯酰胺 (BA)交联共聚 ,制备了含有功能性羟基的温敏性微凝胶 .微凝胶的去溶胀性能研究表明 ,TREGMA的引入使得微凝胶的体积相转变温度得到提高 ,同时所制得微凝胶具有较好的温敏性 .该类微凝胶有望成为良好的生物医用材料 .Triethyleneglycol monomethacrylate (TREGMA) was synthesized by two steps and characterized using IR and H-1-NMR. It then was copolymerized with N-isopropylacryl-amide (NIPAM) using N, N-methylene bisacrylamide (BA) as crosslinker through surfactant-free emulsion polymerization to prepare temperature-sensitive microgels containing functional hydroxy groups. Investigation on the deswelling behavior of the microgels indicated that the microgels prepared had good temperature sensitivity, and the incorporation of TREGMA made the volume-phase transition temperature of the microgels shifted to higher temperature. This type of microgels might be good candidate for biomedical materials.

关 键 词：聚(N-异丙基丙烯酰胺) 性能研究 功能性 制备 羟基 亚甲基双丙烯酰胺 无皂乳液聚合法 甲基丙烯酸酯 二缩三乙二醇 温敏性微凝胶 生物医用材料 相转变温度 合成路线 交联共聚 体积 

分 类 号：TQ427[化学工程]