应用定量组织速度成像技术和组织追踪法研究急性期川崎病患儿左心收缩功能  

Assessment of Left Ventricular Function in Children with Acute Kawasaki Desease by Quantitative Tissue Velocity Imaging and Tissue Tracking

作　　者：刘静华[1] 邓又斌[1] 杨好意[1] 毕小军[1] 常青[1] 黎春雷[1] 王宏伟[2] 

机构地区：[1]华中科技大学同济医学院附属同济医院超声影像科,武汉市430030 [2]华中科技大学同济医学院附属同济医院小儿科,武汉市430030

出　　处：《中国超声医学杂志》2005年第5期367-369,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的应用定量组织速度成像技术和组织追踪法研究急性期川崎病(Kd)患儿左心收缩功能,以寻求川崎病早期心脏损害的诊断指标。方法通过M-型超声获得左室射血分数(EF);应用定量组织速度成像技术和组织追踪分析软件测量31例急性期川崎病患儿与20例正常儿童前间隔、后壁、前壁、下壁、后间隔和侧壁的二尖瓣环处、基底部和中间部的收缩期峰值速度(Vs)、收缩期最大位移(D),并比较两组间各参数。结果患儿组左室射血分数与正常组相比无统计学差异;患儿组各室壁的二尖瓣环处和部分室壁的基底部、中间部的Vs低于正常组(P<0.05)。6个室壁的平均Vs在二尖瓣环水平、基底部和中间部两组间均有统计学差异(P<0.05)。患儿各室壁各节段的收缩期最大位移均低于正常儿童,在所有二尖瓣环水平和部分室壁基底部、中间部两组间有统计学差异(P<0.05)。结论川崎病急性期左室整体和部分室壁局部收缩功能受损;定量组织速度成像技术和组织追踪法能够定量急性期川崎病左室功能改变。Objective To assess the left ventricular(LV) function in children with acute Kawasaki disease (Kd) by quantitative tissue velocity imaging(QTVI) and tissue tracking(TT).Methods Twenty healthy subjects and thirty-one children with acute Kawasaki disease were studied with QTVI and TT.Off-line LV regional velocity and displacement profiles along LV apical long-axis view,apical two-chamber view and four-chamber view were obtained synchronously.The peak systolic displacement (D) and the peak systolic velocities(Vs) from posteroseptal,lateral,anteroseptal,posterior,anterior and inferior wall were measured.Results The Vs and displacement of every wall at mitral annular level and some segments in Kd children was lower than that in healthy children (P<0.05).Conclusions The left ventricular longitudinal systolic function was impaired although left ventricular ejection fraction was normal in acute Kd children.

关 键 词：定量组织速度成像技术 左心收缩功能 组织追踪法 川崎病 急性期 患儿 左室射血分数 统计学差异 收缩期峰值速度 二尖瓣环 正常儿童 M-型超声 基底部 诊断指标 心脏损害 分析软件 功能受损 局部收缩 左室整体 功能改变 正常组 

分 类 号：R725.4[医药卫生—儿科]