体外循环下冠状动脉搭桥术中经颅多谱勒高强度短信号与术后神经心理学功能变化的关系(英文)  

The correlation between postoperative neuropsychological changes and the number of HITS by TCD during coronary artery bypass surgery

作　　者：严敏[1] 戴安卢[1] Andreas Boning Sven Carstensen Jorg Kampen Peter H.Tonner Jens Scholz Berthold Bein 

机构地区：[1]浙江大学医学院附属第二医院麻醉科,杭州310009 [2]德国基尔大学医学院麻醉科 [3]德国基尔大学医学院心胸外科

出　　处：《中华急诊医学杂志》2005年第5期357-361,共5页Chinese Journal of Emergency Medicine

摘　　要：目的　评估经颅多谱勒超声(TCD) 监测术中高强度短信号(HITS) 数目能否预测术后神经心理功能变化的程度。方法　20例体外循环下行冠状动脉搭桥术的患者, 术中采用TCD监测HITS的数值, 神经心理学成套测验用于评定术后神经心理学功能的变化。结果　术中HITS的数值与术后神经心理学功能的是否有变化无关。成套测验与HITS的数值的多因素相关分析中发现RW Dg1 DG5 与HITS的数值有微弱相关。结论　体外循环过程中HITS数值的变化与术后神经心理学功能变化无关。Objective To evaluate whether the number of high intensity transient signals(HITS)intraoperative detected by transcranial doppler ultrasound(TCD)can predict postoperative neuropsychological deficit. Methods Twenty patients scheduled for coronary artery bypass grafting(CABG)operation with cardiopulmonary bypass were enrolled in this study.HITS were recorded by TCD intraoperatively.And neuropsychological test battery was used to assess postoperative neuropsychological changes. Results There was no significant difference in the number of HITS compared with patients with or without neuropsychological changes.And multivariable correlation between the test scores and the number of HITS showed there was a weak correlation between RW Dgt-Dg5 and HITS(P<0.05). Conclusion The number of HITS detected during cardiopulmonary bypass(CPB) do not!correlate with the postoperative neuropsychologial changes.

关 键 词：功能变化 体外循环 术后 术中 信号 强度 神经心理学功能 经颅多谱勒超声 冠状动脉搭桥术 多因素相关分析 HITS TCD监测 成套测验 数值 

分 类 号：R654.2[医药卫生—外科学]