氯化3-氯-2-羟丙基三甲基铵的合成  

STUDY ON SYNTHESIS OF 3-CHLORO-2-HYDROXY-PROPYL TRIMETHYL AMMONIUM CHLORIDE

作　　者：孙曰圣[1] 张小林[1] 肖鉴谋[1] 杨期勇[1] 

机构地区：[1]南昌大学化工系,南昌330029

出　　处：《精细石油化工》2004年第2期12-14,共3页Speciality Petrochemicals

摘　　要：研究了三甲胺盐酸盐与环氧氯丙烷在乙醇水溶液中反应生成氯化3 氯 2 羟丙基三甲基铵的工艺条件, 通过正交实验得到的较佳工艺条件为:反应液pH值8～9,反应温度35℃;环氧氯丙烷/三甲胺盐酸盐(摩尔 比)=0.95∶1;反应时间1h。在此条件下,产率达到91%。The technological conditions for synthesized of 3-chloro-2-hydroxypropyl trimethyl ammo- nium chloride from trimethylamine hydrochloride and epichlorohydrin in the alcohol-water media was studied. The optimum reaction conditions were obtained by orthogonal experiments as follows: pH of reaction liquid 89; reaction temperature 35 ℃;n(epichlorohydrin)/n(trimethylamine hydrochloride)=0.95∶1; reaction time 1 h. The yield was 91%.

关 键 词：三甲基铵 羟丙基 氯化 三甲胺盐酸盐 环氧氯丙烷 合成 反应液pH值 工艺条件 乙醇水溶液 反应生成 正交实验 反应温度 反应时间 摩尔比 

分 类 号：TQ463.4[化学工程—制药化工] TQ352.7