用PCR方法检测献血者的HCMV感染情况  

Test of Blood Donors for Human Cytomegalovirus Infection by Polymerase Chain Reaction

作　　者：赵国强[1] 胡志荣[1] 王秀林[1] 苏堤[1] 徐友梅[1] 

机构地区：[1]河南医科大学微生物学与免疫学教研室,450052

出　　处：《中国输血杂志》1994年第2期67-69,共3页Chinese Journal of Blood Transfusion

摘　　要：我们用PCR方法对某医院110名献血者的HCMV感染情况进行了检测和分析。结果发现,献血者中HCMV-DNA阳性率为61.8％(69/110);同时显示出HCMV-DNA阳性率随年龄增大而增高,由于献血者中存在着HCMV高带毒率的现象,建议在免疫缺陷病人,移植者及婴儿等特殊易感人群输血时,应对献血者的血液进行HCMV的检测和筛选。The test of 110 normal blood donors recruited by one hospital for human cytomegalovirus (HCMV) infection was conducted by polymerase chain reaction,with its findings being analysed, indicating that the HCMV-DNA positive rate among the mentioned above blood donors was 61. 8% (68/110) ,in the meantime the HCMV-DNA positive rate was raised as the age increased. In the view of high HCMV infection rate among blood donors, it was recommended that the donor blood should be tested and screened for HCMV,when the special vulnerable cohort such as the patients with immune deficiency and transplanted organs and infants wanted to be transfused with donor's blood.

关 键 词：巨细胞病毒 献血者 聚合酶链反应 

分 类 号：R457[医药卫生—治疗学]