2种苯并吡喃类查尔酮天然产物的全合成  

Total Syntheses of Two Natural Benzopranylchalcones

作　　者：朱燕云[1] 陈希慧[1] 黄初升[2] 刘红星[2] 凌新龙[2] 

机构地区：[1]广西大学化学化工学院,南宁530004 [2]广西师范学院应用化学研究所,南宁530001

出　　处：《应用化学》2005年第5期560-562,共3页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金(20062001);广西自然科学基金(0007016);广西"新世纪十百千人才工程"资金(20012205)资助项目

摘　　要：A concise route for the total syntheses of benzopranylchalcones from 2,4,6-trihydroxyacetophone(3) and citral(8), by means of cyclization, methoxy-protection and aldol-condensation is described. Two benzopranylchalcones, Boesenbergin B(1) and Boesenbergin A(2) were synthesized from 2,4,6-(trihydroxyacetophone)(3), citral(8) and benzaldehyde(9) via the route. The total yields of compounds 1 and 2 were 26% and 11%, respectively. In the cyclization step, the yields of key intermediates 4 and 7 were 40% and 42%, respectively.A concise route for the total syntheses of benzopranylchalcones from 2,4,6-trihydroxyacetophone(3) and citral(8), by means of cyclization, methoxy-protection and aldol-condensation is described. Two benzopranylchalcones, Boesenbergin B(1) and Boesenbergin A(2) were synthesized from 2,4,6-(trihydroxyacetophone)(3), citral(8) and benzaldehyde(9) via the route. The total yields of compounds 1 and 2 were 26% and 11%, respectively. In the cyclization step, the yields of key intermediates 4 and 7 were 40% and 42%, respectively.

关 键 词：全合成 苯并吡喃类查尔酮 三羟基苯乙酮 柠檬醛 苯甲醛 

分 类 号：O621.2[理学—有机化学]