影响骨碎补浸膏中柚皮苷含量的因素研究  

Influence of Different Extraction Conditions on Naringin Content in Drynaria Extract

作　　者：陈丰连[1] 贾薇[1] 曾元儿[1] 

机构地区：[1]广州中医药大学中药学院,广州510405

出　　处：《中药新药与临床药理》2005年第3期210-211,共2页Traditional Chinese Drug Research and Clinical Pharmacology

摘　　要：目的考察不同提取条件对骨碎补浸膏中柚皮苷含量的影响。方法采用高效液相色谱法测定骨碎补中柚皮苷的含量,考察了不同提取溶剂(乙醇和水)、不同烘干温度(60,100,120℃)和时间(0,0.5,1.0,1.5,2.0,5.0,10.0,25.0,50.0h)对骨碎补提取液中柚皮苷含量的影响。结果实验表明,骨碎补浸膏以水为溶剂提取较好,而柚皮苷的损失随烘干温度的升高和时间的延长而增加。结论该研究可为含骨碎补复方制剂的提取工艺、剂型选择和质量标准研究提供参考。Objective To study the different extraction condition on naringin content in Drynaria extract.Methods The Naringin content in Drynaria extract was determined by HPLC.The e ffect of extraction solutions,drying temperature(60℃,100℃and 120℃)and drying time (0,0.5,1.0,1.5,2.0,5.0,10.0,25.0,50.0hours respectively)on naringin content in Drynaria extract was investigated.Results The optimal extraction solution for Drynaria extract was water,and the loss of naringin enhan ced with the increase of drying temperature and the prolongation of dryin g time.Con-clusion The result can provide references fo r the extraction technology,preparation selection and quality control of the compound including Rhizoma Drynariae.

关 键 词：骨碎补浸膏 柚皮苷 高效液相色谱法 提取条件 

分 类 号：R284.2[医药卫生—中药学]