1,3-偶极环加成合成新型3a,6a-二氢-4,6-二氧代吡咯啉并[3,4-d]吡唑类衍生物  

Synthesis of New 3a,6a-Dihydro-4,6-dioxopyrrolo[3,4-d]pyrazole Derivatives by 1,3-Dipolar Cycloaddition Reaction

作　　者：解正峰[1] 刘方明[1] 貊雪霞[1] 惠永海[1] 孙亚栋[1] 

机构地区：[1]新疆大学化学化工学院,乌鲁木齐830046

出　　处：《有机化学》2005年第6期696-699,共4页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.29702007;20162004)资助项目.

摘　　要：α-氯代-4-氧代-4H-1-苯并吡喃-3-甲醛芳腙与N-取代苯基-马来酰亚胺在三乙胺作用下通过1,3-偶极环加成合成了一系列含3-(4-氧代-4H-1-苯并吡喃-3-基)-3a,6a-二氢-4,6-二氧代吡咯啉并[3,4-d]吡唑类衍生物.化合物结构经元素分析,IR,1HNMR及MS确证.A series of new 3-(4-oxo-4H-benzopyran-3-yl)-3a,6a-dihydro-4,6-dioxopyrrolo[3,4-d]pyrazoles have been synthesized by the reaction of N-arylmaleimides with nitrile imines, prepared from α-chloro4-oxo-4H-benzopyran-3-carboxaldehyde arylhydrazone in situ, through 1,3-dipolar cycloaddition reaction. The structures of all these new compounds were confirmed by elemental analysis, IR, H-1 NMR and MS spectra.

关 键 词：偶极环加成 二氧代 衍生物 吡唑类 合成 二氢 吡咯 苯并吡喃 马来酰亚胺 化合物结构 取代苯基 元素分析 三乙胺 ^1H NMR IR 

分 类 号：O626.1[理学—有机化学]