铜绿假单胞菌数量阈值与细菌耐药的关系及对策  

The relationship between strategy to pseudomonas aeruginosa quorum sensing and drug resistance

作　　者：李国军[1] 李洪涛[1] 宋建新[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院感染科,湖北武汉430030

出　　处：《医学研究生学报》2005年第5期447-450,共4页Journal of Medical Postgraduates

摘　　要：作者综述了铜绿假单胞菌数量阈值系统的组成、铜绿假单胞菌的主要耐药机制以及两者的关系,并介绍了通过多种途径干扰数量阈值系统,以减弱细菌耐药性的方法,这将为控制细菌感染提供新的有效途径。This paper underlines the composition of OS(Quorum Sensing) systems in Pesudomonas aeruginosa,the resistance mechanism of Pesudomonas aeruginosa and the relevance between QS systems and the resistance mechanism.What's more,it introduces several pathways of the interfering of QS systems to weaken the resistance.These will show a new prospect to the control of bacterial infection.

关 键 词：铜绿假单胞菌 阈值感应 耐药 

分 类 号：R378.99[医药卫生—病原生物学]