自体全厚皮片移植后黑色素细胞密度的动态变化  

ABSTRACTSTHE DYNAMIC CHANGES OF DENSITY OF EPIDERMAL MELANOCYTES IN THEAUTOGRAFT OF SKIN

作　　者：李海洋[1] 赵文清 郑信民 

机构地区：[1]山东滨洲医学院附属医院口腔颌面外科,西安医科学口腔医学院颌面成形外科

出　　处：《中国修复重建外科杂志》1994年第2期92-95,共4页Chinese Journal of Reparative and Reconstructive Surgery

摘　　要：应用组织化学及放射自显影技术，对豚鼠自体全厚皮片移植术后３个月内的不同阶段，皮片表皮内黑色素细胞密度的动态变化规律进行了观察。实验表明：表皮颜色的变化与其表皮内黑色素细胞密度改变呈明显的同步关系，且表皮内黑色素细胞对Ｈ－ＴｄＲ的摄取增加。黑色素细胞密度的增加可能在皮片过度色素沉着的形成过程中起重要作用。he dynamic changeS of density of epidermal melanocytes in the full-thickness autografts of skinon guinea pigs were investigated by means of histochamical and autoradiographic techniques at variousjntervals during 3 months peried potoperatively,It was found that the increase of epidermalmelaneeytes was accompanied by hyperpigmentation of the skin grafts. Meanwhils,the amount of 3H-TdR taken by the melanocytes was increased. The results showed that the melanocytes poitive to Dopabecame greater by means of mitoses and activation of inactivated melanocytes(melanoclasts) indensity.The greater density of epidermal melanocytes might play an important role in the developmentof hyperpigmentation on the skin grafts.

关 键 词：黑色素细胞 全厚皮片 皮肤移植 

分 类 号：R622.1[医药卫生—整形外科]