血清免疫球蛋白水平与儿童少年血压的关系  

Relationship Between Immunoglobulins and Blood Pressure in Children and Adolescents

作　　者：王文英[1] 宋力[2] 耿沛阳 王震维[1] 汪玲[1] 刘建中[1] 

机构地区：[1]上海医科大学儿童少年卫生学教研室,200032 [2]北京医科大学儿童少年卫生研究所

出　　处：《中国学校卫生》1994年第4期247-248,共2页Chinese Journal of School Health

摘　　要：为了解原发性高血压与机体免疫状态改变之间的因果关系，本研究应用了单向免疫扩散法对57名血压偏高儿童（血压持续高于其年龄标准的第90百分位数）及58名血压正常儿童的血清IgG，IgA和IgM水平进行了比较，结果显示，两组儿童的三种免疫球蛋白水平均无显著差异。提出在高血压病早期并不存在血清免疫球蛋白的改变，故认为血清免疫球蛋白不适于作为原发性高血压的早期识别指标。In order to identify effect of immunological mechanism on the pathogenesis of hypertension, the serum IgG, IgA, IgM were determined in 58 mild hypertension and 57 normotensive children aged 7- 18 years by the single radial diffusion techniques. The difference were not significant between 2 groups in immunoglobulins (18. 01- 10. 53 vs. 17. 59- 8. 37 for IgG, 1. 54- 0. 84 vs. 1. 46- 0. 63 for 'IgA, 1. 11-0. 64 vs. 1. 48-0. 75mg/ml for IgM). The results indicated that the immunoglobulins were not involved in the pathogenesis of essential hypertension. So serum immunoglobulins are not suitable to be predictors of essential hypertension.

关 键 词：免疫球蛋白 原发性 高血压 儿童 

分 类 号：R725.441[医药卫生—儿科]