正压通气治疗慢阻肺呼衰的临床研究  

Study on type II respiratory failure in COPD treated by BiPAP

作　　者：王秀芬[1] 叶永青[1] 

机构地区：[1]安徽省六安市人民医院呼吸科,237005

出　　处：《临床肺科杂志》2005年第4期475-476,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的观察经鼻(面)罩双水平正压通气(BiPAP)治疗慢性阻塞性肺疾病(COPD)合并型呼吸衰竭的疗效。方法对COPD合并型呼吸衰竭30例行BiPAP治疗,以同期同等病情患者28例做对照。治疗组每日通气治疗2次,每次2小时,共7天,监测其治疗前后的血气变化,对结果进行统计学处理。结果两组治疗后动脉血氧分压(PaO2)及动脉血氧饱和度(SaO2)均有明显上升(P<0.01),动脉血CO2分压(PaCO2)虽均有下降,但治疗组较对照组下降幅度更明显(P<0.01),临床症状改善更显著。结论BiPAP治疗COPD合并型呼吸衰竭疗效显著,操作简单,并发症少,患者易于接受,值得临床推广。Objective To study the effect of BiPAP via nazal/facial mask on type II respiratory failure in COPD. Methods Thirty COPD patients with type II respiratory failure were treated by BiPAP, another 28 similar patients treated by conventional therapy were served as control.The test group was treated by mask ventilation 2 hours every time and twice daily for a week. The arterial blood gas of all were monitored in pre/post-therapy as well. Results After the therapy, all had markedly higher PaO2 and SaO2 (P<0.01), and lower PaCO2 than before. But the test group had the lowest PaCO2 in the two groups.Conclusion The effect of BiPAP on type II respiratory failure in COPD is better than that of conventional way. It is an easily performed and well-compliant artificial ventilation mode.

关 键 词：正压通气 慢阻肺呼衰 COPD BIPAP 呼吸困难 

分 类 号：R563.9[医药卫生—呼吸系统]