甲状腺粗针穿刺活检临床研究  

A STUDY ON CLINICAL SIGNIFICANCE OF COARSE NEEDLE BIOPSY IN THYROID

作　　者：蒋岚[1] 朱建华[1] 徐勇[1] 李春林[1] 

机构地区：[1]泸州医学院附属医院内分泌科,四川泸州646000

出　　处：《泸州医学院学报》2005年第3期235-236,共2页Journal of Luzhou Medical College

摘　　要：目的:探讨粗针穿刺活检在甲状腺疾病诊断中的临床意义。方法:采用Tru-Cut活检针,对52例难于诊断的甲状腺疾病患者给予甲状腺粗针穿刺活检(CNB),并测定甲状腺球蛋白抗体(TGAb)和甲状腺过氧化物酶抗体(TPOAb)。结果:CNB穿刺成功率100%,病理诊断率100%,活检前临床与组织病理诊断符合率71.2%,16.7%以上桥本氏甲状腺炎患者甲状腺自身抗体TGAb和TPOAb测定结果阴性。无严重穿刺并发症。结论:甲状腺疾病诊断不肯定时可应用CNB,CNB是一种全面诊断甲状腺疾病简便、安全可靠的方法。Objective: To investigate the clinical significance of coarse needle biopsy in the diagnosis of thyroid diseases. Methods: 52 patiens with uncertainly diagnostic thyroid disease were treated by coarse needle biopsy (CNB) of thyroid, the clinical diagnosis and histopathologic diagnosis were then compared in all patients, and the circulating autoantibodies TGAb and TPOAb were determined. Results: Of the 52 CNB cases, all biopsies were successfully performed with Tru-Cut bioptic needle, 52 samples (100%) were adequate for histopathologic diagnosis. The accuracy rate of prebioptic diagnosis was 71.2% contrasted to histopathology. More than 16.7% of the circulating autoantibodies TGAb and TPOAb were negative in histologically diagnosed Hashimoto's thyroiditis. There were no bioptic complications. Conclusion: Analysis of the results indicates that CNB is a feasible method for patients with atypical thyroid disease, which is difficult to diagnose. So CNB is a simple, safe, reliable and overall diagnostic method in thyroid diseases.

关 键 词：甲状腺疾病 活组织检查 针吸 

分 类 号：R581[医药卫生—内分泌]