高效液相色谱法测定糖浆剂中扑尔敏与伪麻黄碱的含量  

Determination of the Concentration of Chlorphenamine and Pseudoepherine in Syrup by HPLC

作　　者：张晔[1] 毛磊[1] 于文力 胡昌[1] 

机构地区：[1]中国医药研究开发中心

出　　处：《中国药科大学学报》1994年第1期29-31,共3页Journal of China Pharmaceutical University

摘　　要：采用高效液相色谱法测定了抗感冒糖浆剂中扑尔敏与伪麻黄碱的含量。方法以扑热息痛做内标，扑尔敏的回收率为９９．４３％（ｎ＝５），伪麻黄碱的回收率为９９．６４％（ｎ＝５）。A sensitive and simplified high ferformance liquid chromatographic proced ure has been developed to determine chlorphenamine and pse udoepherine in syr up used for the treatment of cold. The recoveries are 99. 43%and 9 9.64%。 Paracetamol was used as internal standard and the detector wavelength was 210 nm. The method can also be used in the determination of the concentration of chlorphenamine and pseudoepherine of other complex formulations.

关 键 词：含量测定 扑尔敏 伪麻黄碱 

分 类 号：R927.2[医药卫生—药学]