烷基膦酸二正己酯的合成及折光率研究  

SYNTHESES AND REFRACTION OF DI-n-HEXYL ALKYLPHOSPHONATES

作　　者：胡文祥[1] 袁承业[1] 

机构地区：[1]军事医学科学院毒物药物研究所,中国科学院上海有机化学研究所

出　　处：《中国药物化学杂志》1994年第1期51-56,共6页Chinese Journal of Medicinal Chemistry

基　　金：国家自然科学基金

摘　　要：用Ｍｉｃｈａｅｌｉｓ－Ｂｅｃｋｅｒ反应合成了８个烷基膦酸二正己酯；并改进方法，利用相转移催化技术合成了４个高位阻烷基膦酸二正己酯；同时还观察到产物折光率的加和性及随温度变化的规律。Di-n-hexyl alkylphosphonates were prepared with the Michaelis-Becker reaction.4 highly hindered alkylphosphonates were synthesized by the modified Michaelis-Becker reaction, using 18-crown ether-6 or quaternary ammonium halides as the phase transfer catalyst.The refraction of many alkylphosphonates were determined and their uarying law was also studied.

关 键 词：烷基膦酸酯 合成 折光率 

分 类 号：TQ225.24[化学工程—有机化工]