深绿山龙眼种子化学成分研究(Ⅰ)  

Chemical constituents of Helicia nilagirica seeds (Ⅰ)

作　　者：刘桂艳[1] 马双成[2] 郑健[2] 张继[2] 林瑞超[2] 

机构地区：[1]北京中医药大学,北京100029 [2]中国药品生物制品检定所,北京100050

出　　处：《中草药》2005年第6期814-817,共4页Chinese Traditional and Herbal Drugs

摘　　要：目的对深绿山龙眼Helicianilagirica种子的化学成分进行研究。方法采用乙醇提取,石油醚、二氯甲烷、正丁醇萃取,硅胶柱色谱分离,通过理化性质和光谱分析鉴定结构。结果从石油醚部分分离鉴定4个化合物:正十六烷酸(Ⅰ)、β-谷甾醇(Ⅱ)、β-谷甾醇-3-O-β-D-吡喃葡萄糖-6′-乙酸酯(Ⅲ)、胡萝卜苷(Ⅳ)。结论以上化合物均为首次从该种植物中分离得到,其中化合物Ⅰ、Ⅲ、Ⅳ为首次从山龙眼属植物中得到,化合物Ⅲ为新的天然产物。Objective To study the chemical constituents of Helicia nilagirica. Methods The ethanol extract was seperated by petroleum ether, dichloromethane, and n-butanol in sequence, then isolated by silica gel column chromatography. The structures were identified and elucidated by physicochemical pro-(perties) and spectral analysis. Results Four compounds were isolated from the petroleum ether extract and identified as n-hexadecane acid (Ⅰ), β-sitosterol (Ⅱ), β-sitosterol-3-O-β-D-glucoside-6′-acetate (Ⅲ), and daucosterol (Ⅳ). Conclusion All the compounds are isolated from the plant for the first time. Compounds Ⅰ, Ⅲ, Ⅳ are isolated from the plants of Helicia Lour. for the first time, and compound Ⅲ is a new natural product.

关 键 词：山龙眼属 深绿山龙眼 β-谷甾醇-3-O-β-D-吡喃葡萄糖-6′-乙酸酯 

分 类 号：R284.1[医药卫生—中药学]