中国汉族谷胱甘肽转移酶μ基因缺损频度及其遗传特性  

GSTμ Gene Deletion and Hereditary Characteristics in the Han Nationality of China

作　　者：孙贵范[1] 皮静波[1] 郑全美[1] 

机构地区：[1]中国医科大学卫生保健科

出　　处：《中国医科大学学报》1994年第2期104-107,共4页Journal of China Medical University

摘　　要：采用ＰＣＲ方法，对１０４例中国汉族健康人及１０个家庭的亲子代谷胱甘肽转移酶１（ＧＳＴμ）基因进行了检测，发现ＧＳＴμ基因缺损（ＧＳＴ１－０纯合子）率为５１．９％，其中男５２．４％，女５１．２％，男女无显著差异。亲子代遗传分析证明，ＧＳＴμ符合常染色体显性遗传特征。n this study , we used PCR method to detect GSTμ gene in 104 Chinese of Han nationality and 10families. The results showed that GSTμgene deletion(homozygous GST1-0 genotype )in male,femaleand total were 52.4%,51.2%and 51.9%,respectively,and there was no significant difference betweenmale and female.Analysis of GST1 in parents and their children proved that GST1 expressed autosomaldominant inheritance.

关 键 词：谷胱甘肽转移酶 基因 基因缺损 

分 类 号：Q342[生物学—遗传学]