舒宁霜中维生素E的鉴别与含量测定  

Identification and Determination of Vitamin E in Shuningshuang

作　　者：冉光炳[1] 林彩[1] 

机构地区：[1]第三军医大学西南医院药学部,重庆400038

出　　处：《中国药业》2005年第5期29-30,共2页China Pharmaceuticals

摘　　要：目的:建立舒宁霜中维生素E的鉴别与含量测定方法。方法:采用薄层色谱法鉴别维生素E,以一阶导数光谱法测定维生素E的含量。结果:维生素E薄层鉴别斑点清晰,与其他组分的斑点分离较好;维生素E含量测定的线性范围为20～120μg/mL,r=0.9993,平均回收率为99.15%,RSD为0.62%。结论:所用方法可消除其他组分的干扰,简便、快速、准确,可用于舒宁霜的质量控制。Objective:To establish the method of identification and determination for Shuningshuang.Methods:Vitamin E was identified by TLC method,determined without separation by the first order derivative spectrophotometry.The detecting wavelength was at 282 nm.Results:Vitamin E can be identified by TLC method.The first order derivative spectrophotometry was linear with range of 20～120 μg/mL(r=0.999 3). The average recovery was 99.15%.Conclusion:This method is simple and good availability for quality control of vitamin E.

关 键 词：薄层色谱法 一阶导数光谱法 维生素E 

分 类 号：R927[医药卫生—药学] R986