马蔺子甲素乳剂的分光光度测定  

SPECTROPHOTOMETRY OF PALLASINE A EMULSION

作　　者：马晋隆[1] 陈瑞珠[1] 

机构地区：[1]上海医药工业研究院

出　　处：《中国医药工业杂志》1994年第2期72-74,共3页Chinese Journal of Pharmaceuticals

摘　　要：利用马蔺子甲素的醌型结构与２，４－二硝基苯肼反应生成马蔺子甲素双－２，４－二硝基苯腙，再在二乙醇胺－吡啶溶液中形成相应的共轭离子，用分光光度法测定马蔺子甲素乳剂的含量，可使其最大吸收波长由２６９ｎｍ转移到６３２ｎｍ，避开了乳剂中豆油和卵磷脂对其含量测定的干扰。本法平均回收率为９９．４８％，变异系数为０．２３％。The pallasine A reacts with 2,4-dinitrophenylhydrazine to form pallasine A-bis-2, 4-dinitrophenylhydrazone.It forms further a corresponding conjugated ion in diethanolamine-pyridine solution, and its λ_(max) remove from 269nm to 632nm. Therefore this method can aviod interference of the soybean oil and lecithin in the emulsion and used for the determination of the pallasine A.The average recovery was 99.48% The cv was 0.23%.

关 键 词：马蔺子甲素 乳剂测定 分光光度法 

分 类 号：R927.2[医药卫生—药学]