阿霉素磁性明胶微球的制备及特性研究  

PREPARATION AND CHARACTERS OF ADRIAMYCIN MAGNETIC GELATIN MICROSPHERES

作　　者：吴传斌[1] 何素梅[1] 高文伟[1] 魏树礼[1] 

机构地区：[1]北京医科大学药学院,中日友好医院,军事医学科学院药物毒物所

出　　处：《中国医药工业杂志》1994年第2期63-66,共4页Chinese Journal of Pharmaceuticals

摘　　要：采用乳化－交联技术制备阿霉素磁性明胶微球，并用荧光分光光度法测定磁性微球中的药量。用原子吸收分光光度法测定磁性微球中磁铁粒子的含量。用振动样品磁强计测定磁性微球的磁性。同时测定了微球粒径大小与分布。The magnetic gelatin microsphere (MG-ms) used in arterial embolization was prepared by emulsion-crosslinking method. The microspheres were digested with HCl-HNO_3 (4:1) mixture, and the α-Fe_2O_3 in MG-ms can be accurately determined by atomic absorption spectrophotometry, Spectrofluorometry was adapted to the quantitation of adriamycin in the Adr-MG-ms.

关 键 词：磁性明胶微球 乳化交联法 阿霉素 

分 类 号：R944.27[医药卫生—药剂学]