不同包衣材料对酮洛芬缓释微丸释药速度的影响  

INFLUENCE OF DIFFERENT COATING MATERIALS ON DRUG RELEASED RATE OF KETOPROFEN PELLETS

作　　者：张焱[1] 陈庆华[1] 

机构地区：[1]上海医药工业研究院

出　　处：《中国医药工业杂志》1994年第8期346-348,共3页Chinese Journal of Pharmaceuticals

摘　　要：以虫胶和聚丙烯酸树脂ＥｕｄｒａｇｉｔＲＳ１００、ＥｕｄｒａｇｉｔＬ１００为包衣材料制备酮洛芬微丸。并就不同衣材对微丸药物体外释放及制剂稳定性的影响进行了比较系统的研究。Two kinds of ketoprofen pellets coated with shellac or polyacrylic acid resin (Eudragit RS 100,Eudragir L100) were prepared.The influence of different coating materials on the drug released rates in vitro and the stability of pellets were studied.

关 键 词：微丸 包衣材料 释放速率 酮洛芬 

分 类 号：TQ463[化学工程—制药化工]