糖尿病并发视网膜病变与伴发周围神经病变的关系探讨  

Relation between diabetic retinopathy and peripheral sensory neuropathy

作　　者：邓金印[1] 杨邦兰[1] 

机构地区：[1]广州军区广州总医院眼科,广州510010

出　　处：《眼科研究》2005年第3期325-326,共2页Chinese Ophthalmic Research

摘　　要：目的探讨糖尿病并发视网膜病变(DR)与伴发周围神经病变(DPN)的相关关系。方法设实验组和对照组,实验组分为有视网膜病变组(DR组)和无视网膜病变组(NDR组)。三组均进行体感诱发电位检查,测定感觉神经传导速度(SCV)。实验组患者根据荧光眼底血管造影(FFA)结果进行分期。结果DR组与对照组间SCV值差异非常显著(P<0.01)。DR组与NDR组比较,SCV值亦有非常显著性差异(P<0.01)。随着视网膜病变的发展由Ⅰ期至Ⅵ期,周围神经病变的发生率逐期递增。结论DR与DPN的发生二者间具有平行关系,DPN的发生率高于DR,所有增殖期DR患者均伴有DPN改变。了解DR与DPN的伴发规律,可能有助于临床对二者病情演变的估计。ObjectiveTo study the relation between diabetic retinopathy (DR) and diabetic peripheral neuropathy (DPN).MethodsNinety-eight cases with DR determined by fundus fluorescin angiography(FFA),31 diabetic patients without diabetic retinopathy (NDR) and 50 volunteers were divided into DR group,NDR group and control group.The sensory nerve conduction velocity (SCV) were measured by electric potential of body sense on all subjects.The SCV was performed based on the FFA results.ResultsSCV was 44.26±6.30,53.23±5.25 and 60.77±4.67 in DR group,NDR group and control group,respectively.There were significant differences in SCV between DR and control group(P<0.01) and DR and NDR(P<0.01).The incidence of peripheral sensory neuropathy was dramatically increased in DR group from stage Ⅰ to Ⅵ.ConclusionIncidence of DPN is correlated with DR.The relation between these two pathologic changes may be valuable to clinical evaluation.

关 键 词：糖尿病性视网膜病变 糖尿病性周围神经病变 眼底荧光血管造影 体感诱发电位 

分 类 号：R587.2[医药卫生—内分泌]