通心络胶囊治疗不稳定型心绞痛的临床效果观察  

Clinical Observation of Curative Effect of Tongxinluo Capsule of Unstable Angina Pectoris

作　　者：李日行[1] 李日健[2] 

机构地区：[1]广东医学院第二附属医院心内科,广东省湛江市524003 [2]广东医学院附属医院心内科

出　　处：《医学理论与实践》2005年第6期629-630,共2页The Journal of Medical Theory and Practice

摘　　要：目的:探讨通心络胶囊治疗不稳定型心绞痛的临床疗效。方法:将60例不稳定型心绞痛患者配对后随机分为2组,对照组给予常规药物治疗,治疗组给予常规药物加通心络胶囊治疗,疗程为8周。通过观察2组患者治疗后血清C反应蛋白、血液流变学的变化及心绞痛发作情况评价疗效。结果:疗程结束后,治疗组血清C反应蛋白及血液流变学指标明显降低(P<0.01),对照组血液流变学指标也有明显改善(P<0.05),治疗组疗程结束后血清C反应蛋白、血液流变学指标及心绞痛发作改善情况与对照组比较,有显著性差异(P<0.01,P<0.05)。结论:通心络胶囊可以降低血清C反应蛋白及血液粘滞性水平,从而改善心肌缺血,是治疗不稳定型心绞痛的有效药物。Objective:To investigate the therapeutic effect of Tongxinluo for unstable angina pectoris. Methods: 60 patients with unstable angina pectoris were randomly divided into two groups. The control group(30cases)was treated with routine therapy,and the treatment group (30cases)was treated with Tongxinluo capsule combined with routine therapy. A treatment course was 8 weeks for both groups. The C reactive protein (CRP) level and Hemorrheology before and after treatment were observed in both groups, and the angina pectoris of patients was observed for 8 weeks. Results: After treatment, CRP level and Hemorrheology in treatment group were increased significantly (P<0.01), and Hemorrheology in control group was increased significantly,too (P<0.05). There were significant differences in CRP level,Hemorrheology and angina pectoris between treatment group and control group after treatment (P<0.01, P<0.05). Conclusion: Tongxinluo capsule can decrease CRP level and the viscosity of blood and improve myocardial ischemia. So it is an effective drug for treating unstable angina pectoris disease.

关 键 词：不稳定型心绞痛 通心络胶囊 临床效果观察 血液流变学指标 血清C反应蛋白 心绞痛发作 常规药物治疗 心绞痛患者 显著性差异 血液粘滞性 对照组 治疗组 临床疗效 改善情况 心肌缺血 有效药物 疗程 治疗后 低血清 白及 

分 类 号：R541.4[医药卫生—心血管疾病] R259.414[医药卫生—内科学]