肾炎益气液对家兔实验性膜性肾小球肾炎的影响  

Effects of Shenyan Yiqiye on Experimental Membranous Glomerulonephritis in Rabbits

作　　者：莫容 魏民[1] 许文忠[1] 朱陵群[1] 靳建华[1] 李克玲[1] 李伯光[1] 贾旭[1] 严京[1] 

机构地区：[1]北京中医药大学病理教研室

出　　处：《中国中西医结合杂志》1994年第5期295-297,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：用阳离子化牛血清白蛋白复制家兔膜性肾小球肾炎及慢性肾功能衰竭的动物模型，选用肾炎益气液进行实验性治疗。结果显示，治疗组尿蛋白和血肌酐明显低于病理组。光镜图像立体学定量分析结果显示，治疗组肾小球平均直径、平均周长、平均表面积、平均体积、平均截面积均小于病理组，肾小球细胞增生数目及毛细血管壁增厚程度皆轻于病理组（Ｐ＜０．０１）。结果提示，肾炎益气液可减轻肾小球病变，改善肾功能。The cationic bovine serum albumin (C-BSA) was used for duplicating experimental animal model of membranous glomerulonephritis with chronic renal failure. Shenyan Yiqiye (SYYQY) was adopted for treatment.The results showed that,in the therapeutic group,the urine protein and serum creatinine were reduced as compared with those in pathological group,P<0.01.The parameter of morphometric analysis of glomeruli such as mean diameter,mean perimeter, mean surface area,mean volume, mean cross sectional area were all decreased,P<0.01,the number of glomerular proliferative cells and thickness of glomerular capillary wall were all attenuated, P<0.01, as compared with those in the pathological group.It suggested that SYYQY might alleviate the glomeruli lesions and benefit the renal functions.

关 键 词：肾小球肾炎 肾炎益气液 治疗 

分 类 号：R692.310.5[医药卫生—泌尿科学]