补肾中药对老年神经－内分泌和免疫系统作用机理的研究  

Research on Effect of Kidney Tonifying Herbs on Senile Neuroendocrine-Immunity

作　　者：张新民[1] 沈自尹[1] 王文健[1] 张玲娟[1] 陈素珍[1] 

机构地区：[1]上海医科大学中西医结合研究所

出　　处：《中国中西医结合杂志》1994年第11期686-688,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：在观察补肾中药对老年人肾上腺皮质储备机能、淋巴细胞糖皮质激素受体作用的基础上，从各内分泌轴不同层次的机能和下丘脑神经递质的变化，探讨了补肾中药的作用机理。认为衰老时机体神经－内分泌和免疫机能的下降系下丘脑在其中起到主导作用。补肾中药对衰老机体神经－内分泌和免疫系统的广泛作用，其关键在于调整了下丘脑的机能失调；补肾中药的作用方式可能是多成份、多环节、多途径、多层次的综合协调作用。Kidney Tonifying Herbs(KTH)exerted their effects on reserve function of the adrenal cortex and Iymphocytic receptor of glucocorticoid.The therapeutic mechanism of KTH was explored with respect of function in endocrine axes and neurotransmitter in hypothalamus.The conclusion was that the senile hypothalamic function played an important role in the declining of neuroendocrine -immunity function.KTH might regulate the function of hypothalamus,delaying the aging of neuroendocrine-immunity disturbance.The way of KTH effect might be the function of comprehensive coordination of the multicomponents,multilayers,multilinks and multipathways.

关 键 词：补肾中药 老年 神经内分泌 免疫 神经递质 

分 类 号：R285.6[医药卫生—中药学]