环孢素A慢性肾毒性患者的中医病机证候特点初探  

The Study of TCM Syndrome on the Patients with Chronic Nephrotoxicity Induced by CsA

作　　者：刘洲[1] 周胜 姚晓峰[1] 孝晨[1] 缪新文[1] 毕革文[1] 张靖[1] 

机构地区：[1]广州中医药大学祈福医院肾脏中心,广州511495 [2]广东省佛山市南海金沙医院,佛山528223

出　　处：《中国中西医结合肾病杂志》2005年第6期347-350,共4页Chinese Journal of Integrated Traditional and Western Nephrology

基　　金：广东省中医药管理局科研项目 (No .10 0 0 5 4)

摘　　要：目的:探讨环孢素A(CsA)慢性肾毒性的中医病机、证候特点。方法:对广州地区部分开展肾移植单位的30例肾移植术后CsA慢性肾毒性患者,采用流行病学调查方法,结合聚类分析总结该类患者的中医病机证候特点。结果:30例患者被聚为三类,第一类患者以肾阴虚及湿热证为主;第二类患者以肾阴虚及血瘀证为主;第三类患者无统计学意义。结论:CsA慢性肾毒性的中医病机主要为肾阴虚夹湿热、瘀血。Objective:To study the TCM syndrome of patients with chronic nephrotoxicity induced by Cyclosproine A (CsA).Methods:30 patients diagnosed as chronic nephrotoxicity induced by CsA following renal transplantation in Guangzhou were studied using epidemiologic method and clustering sample analysis.Results:30 patients were divided into 3 types.The characteristics of the first type was kidney yin vacuity and damp-heat.The feature of second type was kidney yin vacuity and blood stasis.The pattern features of the third type were not statistically significant.Conclusion:The pathomechanical features of chronic nephrotoxicity induced by Cyclosproine A were kidney yin vacuity with damp-heat and blood stasis.

关 键 词：环孢素A 慢性肾毒性 中医病机 证候 CSA 聚类分析 

分 类 号：R277.5[医药卫生—中医学]