甲基强的松龙大剂量冲击疗法治疗系统性红斑狼疮48例  

Clinical Analysis of 48 Cases of SLE Treated with Ictus Treatment of Large Dose Methylprednisolone

作　　者：于华[1] 刘璐[1] 刘世萍[1] 

机构地区：[1]哈尔滨医科大学第一临床医学院,黑龙江哈尔滨150001

出　　处：《中国药业》2005年第6期74-75,共2页China Pharmaceuticals

摘　　要：目的:观察甲基强的松龙大剂量冲击疗法的临床疗效。方法:对48例系统性红斑狼疮的疗效进行分析。结果:采用冲击疗法治疗的36例患者中,好转31例(86.1%),无效4例(11.1%),死亡1例(2.8%);常规激素治疗的12例患者中,好转7例(58.3%),无效(16.7%),死亡3例(25%)。结论:甲基强的松龙大剂量冲击疗法在疗效方面优于常规激素疗法。Objective:To observe the therapeutic effect of ictus treatment of large dose methylprednisolone on SLE and to compare the effect with that of routine hormonotherapy.Methods:The therapeutic effects in 48 cases of SLE,were analysed.Results:Among 36 cases receiving ictus treatment of large dose methylprednisolone,31 improved(86.1%),4 failed(11.1%)and 1 died(2.8%):among 12 cases receiving routine hormonotherapy,7 improved(58.3%),2 failed(16.7%)and 3 died (25%).Conclusion:The ictus treatment of large dose methylprednisolone is superior to routine hormonotherapy in therapeutic effect.

关 键 词：大剂量冲击疗法 甲基强的松龙 系统性红斑狼疮 疗效 

分 类 号：R969.4[医药卫生—药理学] R977.11[医药卫生—药学]