军团菌与肺心病感染关系的研究  

A STUDY ON THE RELATIONSHIP BETWEEN LEGIONELLA AND COR PULMONALE

作　　者：宋满景[1] 冀锐锋[1] 刘卓拉[1] 王俊升[1] 王淑萍[1] 米亚英[1] 

机构地区：[1]山西医学院第二附属医院,山西医学院

出　　处：《中华传染病杂志》1994年第3期137-140,共4页Chinese Journal of Infectious Diseases

摘　　要：用ＥＬＩＳＡ法对慢性肺原性心脏病（肺心病）及其他内科患者３３２例的军团菌９个菌种１７个血清型ｌｇＧ抗体进行检测。结果发现，阳性率为４３．６７％，感染率为１３．５５％。备组阳性率：肺心病组４７．９１％，肺炎组４６．１６％，非肺炎组５８．３３％，均明显高于非呼吸系统疾病组２７．８３％，有显著统计学差异（Ｐ＜０．００５，０．０２，０．００１）。感染率以非肺炎组２６．３８％，肺心病组１５．６２％为高，与非呼吸系统疾病组相比差异有显著性（Ｐ＜０．０２，０．００１）。肺心病病情与军团菌感染间有相关性（Ｐ＜０．０１）。说明军团菌感染与免疫功能低下、暴露机会有关，主要引起呼吸系统疾病。Ｌｐ１、Ｌｐ２、Ｌｍ、Ｌｊ为本地区军团菌感染的主要种、型。By ELISA,serum IgG antibody to Lp1-8,Lm,Ld,Lg,Lb,La,L1, Lf,Lo andLi antigens were measured in patients with cor pulmonale(n=96) and other diseases,including pneumonia (n=67),non-pneumonia(n=72)and non-respiratory disease (n=97).The results showed that the total antibody positive test was in all the patients (n=332)was 43.67% and infection rate was l3.55%。The positive rate in cor pulmonle(47.91%),pneumonia (46.16%)and non-pneumonia (58.33% ),were higher than thatin non-respiratory disease(27.83%),(P<0.005,0.02,0.001, respiectively), The infectionrates in non-pneumonia(26.38%),and cor pulnonale(15.62%)were higher than thatin non-respiratory diseasc(4.12%),(P<0.02,0.001,respectively).Sevcrity of corulmonaie was closely correlated with legionella infection(p<0.0l).These indicatedpthat legionella infection,which mainly cause respiratory disease,may be related tolowered immune function and community exposure,and Lp1,Lp2,Lm,Lj are themajor species of legionella infection in our area.

关 键 词：军团菌 肺心病 病因 

分 类 号：R541.5[医药卫生—心血管疾病]