婴幼儿轮状病毒肠炎肠道菌群的动态变化  

DYNAMIC FLUCTUATION OF GASTROIN-TESTINAL MICROFLORA IN INFANS WITHROTAVIRUS DIARRHEA

作　　者：张琳[1] 邱学 李素娥[1] 

机构地区：[1]石家庄河北医学院第三附属医院儿科

出　　处：《中华儿科杂志》1994年第5期282-284,共3页Chinese Journal of Pediatrics

摘　　要：对３９例轮状病毒腹泻患儿肠道菌群进行定量检查，与３０名健康儿童对照比较，双歧杆菌、拟杆菌、乳杆菌和肠球菌数量显著下降，肠杆菌在菌群中所占比例相对升高，提示肠菌群失调。对其中２０例腹泻患儿进行肠菌群动态定量分析，发现在发病早期即出现肠菌群紊乱，随着腹泻症状消退，肠菌群失调逐渐纠正，而且厌氧菌上升速度较快。提示菌群失调程度与临床病情及脱水程度有关。AbstractThe fecal flora of 39 infants with rotavirusdiairhea were studied. As compared with 30 healthychildren, thequantity of Bifidobacteria, Bacteroides,Lactobacillus and Enterococcus diminished, while thatof Enterobacteriae increased relatively. To understandthe function of gastrointestinal microflorain diarrheaand to search for new therapy for diarrhea, we ob-served dynamically the quantity of intestinal flora in20 cases with rotavirus diarrhea at the early stage ofdiairhea till the seventh day after recovery. The resultsshowed that disturbance of enteric flora oecurred atthe early stage and as diarrhea improved theoragradvally beeame noimal and anaerobic bacteriaincrearsesl rapidly. The degree of disturbance of florawas related the symptonis and extent of dehydration.The anaerobic bacteria played important roles in theseverity, course and prognosis of rotavirus diarrhea.

关 键 词：轮状病毒 腹泻 肠道菌群 婴幼儿 

分 类 号：R725.125[医药卫生—儿科]