低分子肝素联合尿激酶治疗频发短暂性脑缺血  

The Treatment of Recurrent TIA with the Combination of LMWH and Urokinase--A Clinical Study

作　　者：汪志云[1] 刘国萍[1] 叶文翔[1] 

机构地区：[1]天津市第一中心医院神经内科,天津300192

出　　处：《中国慢性病预防与控制》2005年第3期121-122,共2页Chinese Journal of Prevention and Control of Chronic Diseases

摘　　要：目的探讨低分子肝素联合尿激酶治疗频发短暂性脑缺血(TIA)发作的疗效和安全性。方法将63例频发TIA患者分为治疗组和对照组。治疗组应用低分子肝素联合尿激酶,对照组仅用扩容治疗。观察两组治疗的总有效率及实验室指标(血小板计数、凝血酶原时间、部分凝血酶原时间和纤维蛋白原)。结果治疗组总有效率与对照组比较,差别有统计学意义,治疗前后实验室指标比较,差别无统计学意义。结论应用低分子肝素联合尿激酶治疗频发TIA是一种有效、安全的治疗方法。Objective To discuss the efficacy and security in the use of the combination of LMWH and urokinase in treating recurrent TIA. Method 63 cases of recurrent TIA were divided into 2 groups. In the treating group, LMWH combined with urokinase were given, while in the control group merely hypervolemic treatment was given. The total efficacy of the two groups, including the influences of platelet counts, prothrombin time, partial prothrombin time and fibrinogen had been observed before and after treatment. Results The total efficacy between the two groups was significantly different, but the laboratory items had no significant difference before and after treatment. Conclusion The use of LMWH combined with urokinase in treating recurrent TIA was an efficacious treatment with good security.

关 键 词：低分子肝素 尿激酶 短暂性脑缺血 

分 类 号：R543[医药卫生—心血管疾病]