妊娠期糖耐量降低与妊娠结局关系的前瞻性研究  

Carbohydrate intolerance and pregnancy out-come.

作　　者：孙宝治[1] 王晓光[1] 王运玲[1] 薛立贤 权志强 张益衡 牛评光[1] 

机构地区：[1]青岛市立医院妇产科

出　　处：《中华妇产科杂志》1994年第3期141-143,共3页Chinese Journal of Obstetrics and Gynecology

摘　　要：随机对２８９例孕妇作５０ｇ葡萄糖应激试验（５０ｇＧＣＴ），阳性者进一步作７５ｇ葡萄糖耐量试验（７５ｇＧＴＴ），并随访妊娠结局。结果：５０ｇＧＣＴ阳性率为１６．９６％，妊娠期糖耐量降低（ＧＩＧＴ）患病率为５．１９％，妊娠期糖尿病（ＧＤＭ）患病率为１．７３％；ＧＩＧＴ及ＧＤＭ孕妇中，好高征、胎膜早破、巨大儿、手术产、新生儿患病等的发生率明显增加；５０ｇＧＣＴ时孕妇血糖水平与新中儿出生体重呈正相关。提示：妊娠期可发生不同程度的糖耐量降低，并由此导致孕产妇及胎婴儿病率增加；ＧＤＭ的诊断标准应以孕产妇和胎婴儿异常为依据。ifty gram oral glucose challenge test (50g GCT)was performed, as a screening test of diabetes mellitus(DM), in 289 pregnant women. and further. a 75g oralglucose tolerance test(OGTT) was done in thosewomen with glucosc level≥7. 78 mmol/L.The re- sults showed that 49 women had a glucose level≥7.78mmol / L(16.96%),among whom 15(5.19%)wereidentified as having gestational impaired glucose to-lerance (GIGT). and 5(1.73%) had gestational diabetes mellitus(GDM) as diagnosed by 75g OGTT. The prevalence of PIH, premature rupture of membrance,fetal macrosomia,cesareran section、 perinatal morbidity were higher in GIGT and GDM mothers and there was a positive correlation between glucose level of 50g GCT and the birth weight ofnewborns. It suggested that 50g GCT may be a prefer- able screening test for GDM since it is simple and cheap with high sensitivity,and specificity.

关 键 词：糖尿病 妊娠 糖耐量试验 胰岛素 

分 类 号：R714.256[医药卫生—妇产科学]