肾移植术后真菌感染诊治体会  

Diagnosis and treatment of fungal infection following renal transplantation

作　　者：李远明[1] 叶启发[1] 伍锟[1] 赵学义[1] 郝胜华[1] 明英姿[1] 刘斌[1] 

机构地区：[1]中南大学湘雅三医院湘雅移植医学研究院,湖南长沙410013

出　　处：《中国现代医学杂志》2005年第10期1572-1574,共3页China Journal of Modern Medicine

摘　　要：目的探讨肾移植术后真菌感染的临床防治措施。方法回顾性分析48肾移植术后感染患者中,16例继发肺部真菌感染患者的临床资料。结果合并真菌感染多与使用多联广谱抗生素及大量激素有关。真菌类型多为白色念珠菌,使用氟康唑序贯性方法治疗肺部真菌感染者安全、可靠。结论降低继发真菌感染发病率的主要途径是避免盲目使用高效多联广谱抗生素及糖皮质激素,定期进行多途径的真菌检查和培养;早期发现真菌侵袭,早期采取相应措施,使肾移植患者真菌感染的危险减少到最低限度,从而提高移植成功率。[Objective] To investigate the measure of prevention and cure of fun gal infection following renal transplantation. [Method] In 48 cases of infect ion after renal transplantation, the clinical data of 16 cases with the secondar y pulmonary fungal infection were retrospectively analyzed. [Result] Patients of the secondary pulmonary fungal infection were utilization of broad spectrum a ntibiotics and corticosteroids. Candia albicans was ranked as the first pathogen . It was safe and reliable of using fluconazole stepply to treat the secondary p ulmonary fungal infection [Conclusion] The best approach to reduce the inciden ce rate of secondary pulmonary fungal infection is to avoid abuse of broad spect rum antibiotics and corticosteroids. Examine periodically, discover early, treat early. Only by these ways can we decease the danger of fungal infection in rena l transplantation extremely, so as to incease the success rate of transplantatio n.

关 键 词：肾移植 真菌感染 

分 类 号：R699.2[医药卫生—泌尿科学]