骨钙素RIA试剂盒研制及其临床应用  

THE DEVELOPMENT AND CLINICAL APPLICATION OF A RADIOIMMUNOASSAY FOR SERUM BGP

作　　者：杨梅芳[1] 李振甲[1] 朱守荣[1] 何绍贵[1] 张玉娥[1] 马三元[1] 皇甫立云[1] 

机构地区：[1]中国人民解放军总医院基础所生化研究室,沈阳军区总医院,新疆医学院附属医院,安徽省武警总队医院

出　　处：《中华核医学杂志》1994年第3期167-169,共3页Chinese Journal of Nuclear Medicine

摘　　要：应用自行研制组装的血清骨钙素（ＢＧＰ）ＲＩＡ试剂盒，对１４４例正常人和１７６例不同骨病患者的血清ＢＧＰ含量进行了测定．结果显示，血中ＢＧＰ含量的升降，反映了不同骨病时成骨细胞的功能状态，表明ＢＧＰ与骨疾病的发生有密切关系．这对研究骨病的发病机理、诊断和疗效分析，提供了一项有意义的指标．Abstract The serum BGP levels of various kinds of osteal disorders (n= 198), including ostarthroc rigidity,osteodeformity, osteotuberculosis, osteoporosis, rickets, osteoma, uremia diabetes, hyperthyroidism and pregnancy were measured and compared with a control group of healthy subjects (n= 144) by using a RIA protocol devised by ourselves. The results revealed that the change of serum BGP levels was closely related to osteopathy occurrence and might reflect the different function stages of osteoblasts.

关 键 词：骨疾病 诊断 放射免疫测定 

分 类 号：R681.04[医药卫生—骨科学]