空腹血清CGRIA在妊娠期肝内胆汁淤积症中的价值  

VALUE OF FASTING SERUM CLYCOCHOLIC ACID RADIOIMMUNOASSAY IN THE DIAGNOSIS OF INTRAHEPATIC CHOLESTASIS OF PREGNANCY

作　　者：王福淇[1] 江明礼[1] 张黎铭[1] 黄耀章[1] 

机构地区：[1]上海市第一人民医院核医学科,上海市第一人民医院产科

出　　处：《中华核医学杂志》1994年第4期198-199,共2页Chinese Journal of Nuclear Medicine

摘　　要：于１９９０年１月～１９９２年４月采用ＲＩＡ法测定了１６０６名孕妇血清甘胆酸（ＣＧ），结合临床资料其中６３例确诊为孕期肝内胆汁淤积症（ＩＣＰ）．ＣＧ正常值上限为２６４０μｇ／Ｌ，ＩＣＰ的阳性检出率达９８％，发病率３．９％．对ＣＧＲＩＡ测定在ＩＣＰ的诊断．及其与羊水污染及分娩方式的关系作一初步分析和价值评估，ＣＧＲＩＡ测定对ＩＣＰ的早期诊断及胎儿窘迫的预报有重要作用，可降低围产儿的死亡率．Abstract pregnant women admitted to our hospital during January 1990 to April 1992 were detected for their fasting serum glycocholic acid with radioimmunoassay(CG RIA).63 cases of intrahepatic cholestasis of pregnancy (ICP) were diagnosed and verified.The upper limit of normal CG was 2640mg/L,the positive detected rate was 98% and the incidence of ICP was 3.9%.A preliminary analysis was made on its value in the diagnosis of ICP,its relationship to contamination of amniotic fluid and choice of child delivery way.It is found that CG RIA is of value in early diagnosis of ICP,in prediction of fetal distress and hence,is helpful in lowering perinatal mortality.

关 键 词：甘胆酸 放射免疫法 肝汁郁积 肝内 妊娠妇女 

分 类 号：R714.25[医药卫生—妇产科学]