特发性突聋的中西药物和高压氧联合治疗(附66例/70耳分析)  

Utilily of hyperbaril oxyen combined wilh conventonal drugs in treatment for ieliopathic Sudden deafness

作　　者：刘爱珍[1] 陈小维[1] 郭养淳[1] 徐浩文[2] 

机构地区：[1]福建医大附属协和医院,福州350001 [2]福建省龙岩市第一医院

出　　处：《现代康复》1997年第5期334-335,共2页Modern Rehabilitation

摘　　要：自1993年1月至1996年1月，使用中、西药物联合高压氧治疗特发性突聋，并以单纯药物治疗作为对照组，就66例（70耳）进行对比观察。结果表明，联合高压氧组的有效率和语频听阈均值提高幅度都优于对照组（p＜0.05）。无论对照组或联合高压氧组，发病4周内开始治疗者疗效好；联合高压氧组在发病4周以后开始治疗者的疗效，虽然比发病4周内者略差，但仍优于对照组（p＜0．05）。It is believed that ischemia and hypoxemia in the inner ear might be responsible for the pathogenesis of idiopathic sudden deafness (ISD) .In the present study, eligible candidate of ISD were rdmdonly classed into two groups: a) combined hyperbaric oxygen group: 34 cases(36 - ear) were treated wth hyperbaric oxygen combined with conventional drugs.b) control group: the other 32 cases(34 - ear)were treated with the same set of drugs only.Results: 1) the number of cases gaining hearing improvement. and the amount of hearng recovery in combined hyperbaric oxygen group were greater than those in the control (p<0.05). 2) patients in both groups who received treatmeht within four weeks after onset had better hearing results than those started treatment beyond four weeks had .Even in the subgroups of receiving treatment 'after 4 weeks,the hearing results in combined hyperharic oxygen group were better than those in the control(p<0.05).In conclusion, it is author I s opinion that in case of ISD patient attended they should always be regarded as an emergency case. The patient must be hospitalized promptly and start treatment as early as possible after the main check up is finished .In our experience, using hyperbaric oxygen combined wth conventional drugs is the remedy of choice for management of ISD.

关 键 词：特发性突聋 联合治疗 中西药物 单纯药物治疗 耳 96年1月 1993年 高压氧治疗 对照组 对比观察 治疗者 有效率 发病 

分 类 号：R764.437[医药卫生—耳鼻咽喉科] R969.3[医药卫生—临床医学]