接触丙烯腈男工的生殖结局流行病学调查  

AN EPIDEMMIOLOGICAL STUDY ON REPODUCTIVE OUTCOMES 0F MALE WORKERS EXPOSED TO ACRYLONITRILE

作　　者：吴维皑[1] 苏江[1] 黄美媛[1] 王莉娥[1] 吕廉[1] 席力强 蔡世雄[1] 

机构地区：[1]中国预防医学科学院劳动卫生与职业病研究所

出　　处：《中华劳动卫生职业病杂志》1994年第5期261-263,共3页Chinese Journal of Industrial Hygiene and Occupational Diseases

基　　金：卫生部科学基金

摘　　要：采用回顾性队列研究的方法，对５３４名接触丙烯腈的男工进行了职业生殖流行病学调查。结果发现，男工接触丙烯腈明显增加了妻子的异常妊娠结局的发生率。经分层分析表明，接触组妻子的死胎死产、新生儿出生缺陷和自然流产的相对危险度可分别高达４．７３（９５％ｃｌ：１．３５～１６．５３）、３．８９（９５％ＣＩ：１．３２～１１．５１）和２．４６（９５％ＣＩ：１．２３～４．９０），统计学差异显著。其他异常生殖指标及孕期合并症，接触组与对照组间未见显著差异。An epidemiological study on reproductive outcomes for 534 male workers exposed to acrylonitrile and 500 con-trol male workers has been conducted.The results showed that there were marked occupational hazards。By.strati～f1ed analysis,the RR for stillbirth, birth defects and spontaneous abjortion were 4.73(95%CL:l.35～16.53),3. 89(95%CL:1. 32～ll. 51)and 2.46(95%CL:1.23～4. 90)respectively,No statistically significant difference in otherpregnancy outcomes or pregnancy complications were found between exposed group and control group。

关 键 词：丙烯腈 生殖流行病学 男工 

分 类 号：R135.1[医药卫生—劳动卫生]