高压氧对小鼠血清皮质醇、脾T淋巴细胞及其亚群的影响  

Effect of Hyperbaric Oxygen on Serum Cortisol,Spleen Tlymphocyte and Its Subsets in Mice

作　　者：张海鹏[1] 田伟[1] 邓欣[1] 刘志强[1] 郝鸣政[1] 王彦[1] 

机构地区：[1]沈阳中国医科大学病理生理教研室,中国医科大学第一临床学院高压氧科

出　　处：《中华理疗杂志》1994年第2期72-73,共2页Chinese Journal of Physical Therapy

基　　金：国家自然科学基金

摘　　要：正常小鼠（Ｃ（５７）ＢＬ／６）在０．２５ＭＰａ吸９９．２％氧情况下，血清皮质醇含量明显高于对照组；脾淋巴细胞Ｔｈｙ－１、Ｌ３Ｔ４、Ｌｙｔ－２阳性细胞百分率及Ｔｈ／Ｔｓ比值均明显低于对照组。提示高压氧可降低细胞免疫功能，其机理与肾上腺皮质功能增强有关。In this paper,it is observed that the amount of serum cortisol was significantly greater than that of control group,and the positive rate of spleen lymphocyte Thy-1,L3T4,Lyt2 and ratio of Th/Ts were obviously lower than those of control group in the condition of 0.25MPa and 99.2% pure oxygen inhalation.This conclusion suggests that the hyperbaric oxygen may decrease the cellular immunity,which is related with the enhancement of adrenal corticoid function.

关 键 词：高压氧治疗 皮质醇 T细胞 

分 类 号：R459.6[医药卫生—治疗学]