口服转移因子治疗小儿反复呼吸道感染临床和免疫功能观察  

The observation of the clinical curing effect and change of immunity in treating children’s RRI with oral transfer factor

作　　者：李晓玲[1] 

机构地区：[1]福建省龙岩市第一医院儿科,福建龙岩364000

出　　处：《儿科药学杂志》2003年第4期42-43,共2页Journal of Pediatric Pharmacy

摘　　要：目的:探讨口服转移因子(TF)治疗小儿反复呼吸道感染(RRI)临床疗效与免疫功能变化。方法:60例RRI患儿随机分成两组,观察组予口服转移因子,对照组予常规治疗。观察两组临床疗效和口服转移因子前后免疫功能。结果:观察组总有效率明显高于对照组(P<0.01)。观察组治疗后IgG、IgA值明显升高(P<0.01),CD3、CD4较治疗前明显升高(P<0.01、<0.05),CD8较治疗前降低(P<0.01)。结论:口服转移因子可调节RRI患儿的免疫功能,患儿的依从性好。Objective:To observe the clinical curing effect and change of immunity in treating children’s RRI with oral transfer factor.Methods:60children who suffered from RRI were divided into two groups at random.The observed group were given transfer factor and the control one were given routine treatment.After taking the pharmaceutical,the clinical curing effects and children’s immunity were compared.Results:The total efficiency of observed group was even higher than that of the other group(P<0.01).The level of IgG and IgA rose obviously after taking it(P<0.01).The level of CD 3 and CD 4 rose evidently(P<0.01,<0.05).The level of CD 8 became lower than that before taking it(P<0.01).Conclusion:Oral transfer factor can adjust the immunity of children who suffered from RRI.The pa-tients were quite responsive to it.

关 键 词：儿童 反复呼吸道感染 免疫 转移因子 

分 类 号：R979.5[医药卫生—药品] R725.6[医药卫生—药学]