流动注射-氢化物发生-原子吸收法测定中药提取物中微量砷  

Determination of Arsenic in Chinese Herbal Extract by Flow Injection-Hydride Generation-Atomic Absorption Spectrometry

作　　者：邓世林[1] 李新凤[1] 邓富良[1] 梁绍先[1] 

机构地区：[1]中南大学湘雅医学院,长沙410078

出　　处：《中国药科大学学报》2003年第4期338-340,共3页Journal of China Pharmaceutical University

摘　　要：目的 :探讨流动注射 氢化物发生 原子吸收光谱法 (FI HG AAS)测定微量砷时的最佳条件 ,建立中药提取物中微量砷的FI HG AAS分析方法。方法 :流动注射 氢化物发生 原子吸收光谱法。结果 :在优化的工作条件下测定砷的检出限为 0 5 6 μg/L ,线性范围 0 6～ 30 μg/L ,相对标准偏差小于 5 % ,加标回收率为 91%～10 4 %。应用于实际样品中微量砷的测定 ,获得满意结果。结论 :本法克服了传统间断氢化物发生 原子吸收光谱法分析速度慢、样品耗量大、操作繁锁等缺点 ,方法操作简便、快速 ,灵敏度及自动化程度高。AIM:To investigate the various test conditions and effect factors for determination of arsenic by flow injection-hydride generation-atomic absorption spectrometry(FI-HG-AAS)and to develop a method for the determination of arsenic in Chinese herbal extract by flow injection-hydride generation-atomic absorption spectrometry. METHOD:Flow injection-hydride generation-atomic absorption spectrometry. RESULT:The detection limit for arsenic was 0.56 μg/L under optimum conditions. The linear range was 0.6～30 μg/L. The relative standard deviation was less than 5% and the recoveries was 91%～103%. This method has been applied to the determination of arsenic in Chinese herbal extract with satisfactory results. CONCLUSION:This method overcame the problems of slow analysis procedure, large sample consuming amount, complex operation and error easily caused by manual injection speed and injection volume in traditional interval hydride generation-atomic absorption spectrometry. It is simple, rapid, highly sensitive and automatic method.

关 键 词：流动注射氢化物发生-原子吸收光谱法 中药提取物 砷 含量测定 

分 类 号：R284[医药卫生—中药学]